Phenotypes Associated with This Genotype

Genotype
MGI:3511747

• Allelic Composition: Lepr^tm1.1Chua/Lepr^tm1.1Chua
• Genetic Background: involves: 129 * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Obesity in Lepr^tm1Chua/Lepr^tm1Chua mice (center) and normal weight in Lepr^tm1.1Chua/Lepr^tm1.1Chua (left)

growth/size/body

growth/size/body region phenotype ( J:94019 )

N • body weight not significantly different from normal controls

homeostasis/metabolism

decreased circulating glucose level ( J:94019 )

• serum glucose levels in females reduced about 12.9%, serum values otherwise normal

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
obesity		DOID:9970	OMIM:601665	J:94019