Phenotypes Associated with This Genotype

Genotype
MGI:3055418

• Allelic Composition: Myf5^tm1Tajb/Myf5^tm1Tajb; Myod1^tm1Jae/Myod1^tm1Jae
• Genetic Background: involves: 129/Sv * C57BL/6 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:92799 )

• only the double homozygous mutants display postnatal lethality

muscle

abnormal myogenesis ( J:92799 )

• skeletal muscle differentiation is seen at E12.5 however myogenesis is still severely impaired such that mutants essentially lack skeletal muscle at birth

absent skeletal muscle ( J:92799 )

• mutants essentially lack skeletal muscle throughout the body including the head