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Phenotypes Associated with This Genotype
Genotype
MGI:3052685
Allelic
Composition
Pdx1tm1Cvw/Pdx1+
Pbx1tm1Mlc/Pbx1+
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pbx1tm1Mlc mutation (0 available); any Pbx1 mutation (24 available)
Pdx1tm1Cvw mutation (1 available); any Pdx1 mutation (15 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• disrupted architecture, inappropriate cell types interspersed with beta cells

growth/size/body
• 9-10 weeks

homeostasis/metabolism
• onset between 9-10 weeks, progresses to overt diabetes

renal/urinary system

Mouse Models of Human Disease
OMIM ID Ref(s)
Diabetes Mellitus, Noninsulin-Dependent; NIDDM 125853 J:75811


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory