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Phenotypes Associated with This Genotype
Genotype
MGI:3051899
Allelic
Composition		 Krt12tm1Wwk/Krt12tm1Wwk
Genetic
Background		 involves: 129P2/OlaHsd * NIH Black Swiss
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krt12tm1Wwk mutation (1 available); any Krt12 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal corneal epithelium morphology ( J:38023 )
• the superficial epithelial cells are swollen, easily removed with gentle brushing, and lack keratin intermediate filaments
decreased corneal epithelium thickness ( J:38023 )
• the corneal epithelium contains about 3 fewer cell layers and the layers present are not firmly attached to the underlying layers

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory