Phenotypes for En1 MGI:3047087 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	En1^{tm1.1(Wnt1)Wrst}/En1⁺
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
En1^{tm1.1(Wnt1)Wrst} mutation (0 available); any En1 mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:91004 )

• homozygous mutants die at P0

nervous system

increased inferior colliculus size ( J:91004 )

• the volume of the inferior colliculi is increased

• this increase is more pronounced than in En1^{tm1(Wnt1)Wrst} heterozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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