Phenotypes Associated with This Genotype

Genotype
MGI:3045981

• Allelic Composition: Rspo2^ftls/Rspo2⁺
• Genetic Background: involves: FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

cleft secondary palate ( J:83881 )

• observed in 2 of 125 fetuses

endocrine/exocrine glands

ovary cyst ( J:83881 )

♀ • observed in some females

renal/urinary system

delayed kidney development ( J:83881 )

• bilateral supernumerary kidneys observed in some fetuses

single kidney ( J:83881 )

• unilateral absence in some fetuses

reproductive system

ovary cyst ( J:83881 )

♀ • observed in some females

decreased ovulation rate ( J:83881 )

♀ • decreased ovulation rates, possibly due to diminished hormonal responsiveness or ovarian cysts

reduced female fertility ( J:83881 )

♀ • females were found to be fertile until ~4 months of age

digestive/alimentary system

cleft secondary palate ( J:83881 )

• observed in 2 of 125 fetuses

growth/size/body

cleft secondary palate ( J:83881 )

• observed in 2 of 125 fetuses

ovary cyst ( J:83881 )

♀ • observed in some females