Analysis Tools
mortality/aging
|
• approximately two-thirds of heterozygous null mice died before weaning at 21 days postpartum
• poor postnatal viability was confirmed in multiple genetic backgrounds
|
cardiovascular system
hemorrhage
(
J:54469
)
|
• at E9.5, approximately 5% of heterozygotes exhibited a similar hemorrhagic phenotype as homozygotes
|
growth/size/body
|
• heterozygous null mice were one-third smaller than wild-type mice by 5 days of birth
|
