Mouse Genome Informatics
cx
    Dnmt3atm1Enl/Dnmt3atm1Enl
Dnmt3btm1Enl/Dnmt3btm1Enl

involves: 129S4/SvJae * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• die before E11.5

embryogenesis
• embryos do not undergo embryonic turning
• by E8.5 embryos lack somites

Mouse Models of Human Disease
OMIM IDRef(s)
Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome 1; ICF1 242860 J:58298