Mouse Genome Informatics
hm
    Rpsatp1/Rpsatp1
KK
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
cardiovascular system
• calcification as well as massive fibrosis is seen in the right ventricle of these mutants with almost 100% penetrance
• degeneration occurs from week 6 to week 10 after birth and proceeds from the outer part of the right ventricular wall to the inner part
• the left ventricular wall is unaffected
• the duration of ventricular muscle depolarization is prolonged indicating a greater susceptibility to arrhythmia

Mouse Models of Human Disease
OMIM IDRef(s)
Arrhythmogenic Right Ventricular Dysplasia, Familial, 5; ARVD5 604400 J:87868