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Phenotypes Associated with This Genotype
Genotype
MGI:3039683
Allelic
Composition
Rpsatp1/Rpsatp1
Genetic
Background
KK
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rpsatp1 mutation (0 available); any Rpsa mutation (24 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• calcification as well as massive fibrosis is seen in the right ventricle of these mutants with almost 100% penetrance
• degeneration occurs from week 6 to week 10 after birth and proceeds from the outer part of the right ventricular wall to the inner part
• the left ventricular wall is unaffected
• the duration of ventricular muscle depolarization is prolonged indicating a greater susceptibility to arrhythmia


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory