Phenotypes Associated with This Genotype

Genotype
MGI:3038831

• Allelic Composition: Psme3^tm1Tchi/Psme3^tm1Tchi
• Genetic Background: involves: C57BL/6J * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

decreased cell proliferation ( J:89182 )

• mutant embryonic fibroblasts show a reduced growth rate and lower saturation density with a reduced number of actively mitotic cells in S phase and an increased number in G₁ phase

growth/size/body

postnatal growth retardation ( J:89182 )

• after weaning mutants weigh less than wild-type mice and have smaller organ to body weight ratios