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Phenotypes Associated with This Genotype
Genotype
MGI:3037970
Allelic
Composition
Gata1tm6Sho/Y
Genetic
Background
involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata1tm6Sho mutation (4 available); any Gata1 mutation (44 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
N
• mast cell production in the bone marrow is normal
• modest splenomegaly is seen in males
• eosinophils are absent
• erythrocyte number is reduced by 27% in males
• hemoglobin level is reduced in proportion with the reduction in erythrocyte number

immune system
• modest splenomegaly is seen in males
• eosinophils are absent

growth/size/body
• modest splenomegaly is seen in males


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory