Mouse Genome Informatics
hm
    Trfhpx/Trfhpx
BALB/cJ-Trfhpx
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• death by 14 days of age
• injections of purified transferrin, mouse or human serum exteneded life

growth/size

hematopoietic system
• microreticulocytes

homeostasis/metabolism
• increased clearance rates (J:8936)
• increased clearance rate (J:64456)
• progressive hyperferremia
• with iron loading visible in the liver, heart, kidney and pancreas (J:8936)
• with iron loading, visible in the embryonic liver and at 6 months of age in the heart, kidney and pancreas (J:64456)

Mouse Models of Human Disease
OMIM IDRef(s)
Atransferrinemia 209300 J:8936 , J:64456