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Phenotypes Associated with This Genotype
Genotype
MGI:3037942
Allelic
Composition
Trfhpx/Trfhpx
Genetic
Background
BALB/cJ-Trfhpx
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trfhpx mutation (1 available); any Trf mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• death by 14 days of age
• injections of purified transferrin, mouse or human serum exteneded life

growth/size/body

hematopoietic system
• microreticulocytes

homeostasis/metabolism
• increased clearance rates (J:8936)
• increased clearance rate (J:64456)
• progressive hyperferremia
• with iron loading visible in the liver, heart, kidney and pancreas (J:8936)
• with iron loading, visible in the embryonic liver and at 6 months of age in the heart, kidney and pancreas (J:64456)

Mouse Models of Human Disease
OMIM ID Ref(s)
Atransferrinemia 209300 J:8936 , J:64456


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory