Phenotypes Associated with This Genotype

Genotype
MGI:3036541

• Allelic Composition: Prmt1^{Gt(U3BetaGeo)7.4.2Rul}/Prmt1^{Gt(U3BetaGeo)7.4.2Rul}
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:61432 )

• embryos die between E4.5 and E6.5

embryo

embryonic growth arrest ( J:61432 )

• mutant embryos implant into the uterus but fail to develop beyond the early egg cylinder stage

abnormal egg cylinder morphology ( J:61432 )

• at E6.5, mutant egg cylinders appear severely attenuated, are often fragmented and lack an organized two-layered cell structure

absent amniotic folds ( J:61432 )

• no amniotic folds are obseved at E6.5

absent ectoplacental cavity ( J:61432 )

• at E6.5, ectoplacental cavities are not observed

• however, mutant embryos appear to develop normal ectoplacental cones and extraembryonic membranes and make good contact with the uterus

absent proamniotic cavity ( J:61432 )

• at E6.5, proamniotic cavities are not observed

• however, mutant embryos appear to develop normal ectoplacental cones and extraembryonic membranes and make good contact with the uterus

reproductive system

empty decidua capsularis ( J:61432 )

• some empty deciduas are noted at E6.5