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Phenotypes Associated with This Genotype
Genotype
MGI:3036311
Allelic
Composition
Ddb2tm1Linn/Ddb2+
Genetic
Background
involves: 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ddb2tm1Linn mutation (0 available); any Ddb2 mutation (15 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Tumorigenesis analysis and Hisptopathological images

neoplasm
• mutants treated with UV light develop skin tumors at a similar time as wild-type, however once tumors form, tumor development proceeds at a greater rate and mice develop more tumors than controls

integument
• increased incidence of skin tumors after UV-irradiation

Mouse Models of Human Disease
OMIM ID Ref(s)
Xeroderma Pigmentosum, Complementation Group E 278740 J:88125


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory