Analysis Tools
homeostasis/metabolism
|
• males exhibit increased glucose tolerance between 16 and 24 weeks of age
• circulating level of insulin is lower in males in response to the same glucose load
• males exhibit an increase in glucose incorporation into tissue glycogen
|
|
• decrease in blood glucose than wild-type males
• fasting plasma insulin levels in males are lower at 28-30 and 54-56 weeks of age
• male skeletal muscle and liver exhibits enhanced insulin-induced glucose uptake
|
cardiovascular system
|
• 28 week old males exhibit an 18% increase in heart weight
|
growth/size/body
|
• 28 week old males exhibit an 18% increase in heart weight
|
|
• small but significant decrease in body weight for both males (5-10%) and females (5%)
|
hematopoietic system
|
• 28 week old males exhibit a disproportionate decrease (29%) in spleen weight
|
immune system
|
• 28 week old males exhibit a disproportionate decrease (29%) in spleen weight
|
liver/biliary system
|
• 28 week old males exhibit a disproportionate decrease (16%) in liver weight
|
