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Phenotypes Associated with This Genotype
Genotype
MGI:3029147
Allelic
Composition
Tff3tm1Dkpy/Tff3tm1Dkpy
Genetic
Background
involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tff3tm1Dkpy mutation (1 available); any Tff3 mutation (9 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
digestive/alimentary system
• impaired physiological migration of epithelium to mucosal surface
• increased development of colitis (colon ulceration, abscesses, and hemorrhage) after dextran sulfate sodium (DSS) administration

immune system
• increased development of colitis (colon ulceration, abscesses, and hemorrhage) after dextran sulfate sodium (DSS) administration

homeostasis/metabolism
• increased development of colitis (colon ulceration, abscesses, and hemorrhage) after dextran sulfate sodium (DSS) administration
• increased development of bloody diarrhea and death after (DSS) administration
• increased weight loss after (DSS) administration


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory