nervous system
• ectopic proliferating and differentiating cells were noted in the upper posterior region, and the cells were reduced in number in the telencephalic striatum region
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• extensive malformations in embryos exhibiting exencephaly; expansion of the corpus striatum mediale
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• described as malformed
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• open third ventricle
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• epithelia were located below the thalamus; ganglionic eminence appeared rotated towards the midline
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• stenosis apparent
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exencephaly
(
J:72635
)
• 20% of heterozygous embryos exhibit exencephaly
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embryo
• in some embryos exhibit failure of neural fold elevation resulting in failure of neural plate closing and an abnormal brain structure
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• ectopic proliferating and differentiating cells were noted in the upper posterior region, and the cells were reduced in number in the telencephalic striatum region
|