Phenotypes Associated with This Genotype

Genotype
MGI:3028106

• Allelic Composition: Gnai1^tm1Drs/Gnai1⁺
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal learning/memory/conditioning ( J:87423 )

• hippocampal long term memory was perturbed

• spatial memory was normal as determined by a Morris water maze test

abnormal associative learning ( J:87423 )

• cued auditory training and memory extinction were normal

abnormal passive avoidance behavior ( J:87423 )

• partial memory loss at 24 hours

abnormal long-term object recognition memory ( J:87423 )

• object recognition was compromised

nervous system

abnormal long-term potentiation ( J:87423 )

• early phase LTP unaffected

• late phase LTP persistence intermediate between homozygotes and wild-type mice