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Phenotypes Associated with This Genotype
Genotype
MGI:2679674
Allelic
Composition		 Syvn1tm1Tn/Syvn1+
Genetic
Background		 D1.Cg-Syvn1tm1Tn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Syvn1tm1Tn mutation (0 available); any Syvn1 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
increased apoptosis ( J:86009 )
• enhanced apoptosis of synovial cells

immune system
decreased susceptibility to induced arthritis ( J:86009 )
• resistance to collagen-induced arthritis due to enhanced apoptosis of synovial cells

skeleton
decreased susceptibility to induced arthritis ( J:86009 )
• resistance to collagen-induced arthritis due to enhanced apoptosis of synovial cells
abnormal joint morphology ( J:86009 )
• enhanced apoptosis of synovial cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory