Phenotypes Associated with This Genotype

Genotype
MGI:2675842

• Allelic Composition: Gp6^tm1Ware/Gp6^tm1Ware
• Genetic Background: involves: Black Swiss

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

abnormal definitive hematopoiesis ( J:85315 )

abnormal platelet activation ( J:85315 )

• failure of platelets to activate after interacting with type I collagen

decreased platelet aggregation ( J:85315 )

• platelets fail to aggregate

homeostasis/metabolism

abnormal blood coagulation ( J:85315 )

• contrary to expectation, no effect on tail bleeding times was observed

• platelets fail to take part in thrombus formation

abnormal platelet activation ( J:85315 )

• failure of platelets to activate after interacting with type I collagen

decreased platelet aggregation ( J:85315 )

• platelets fail to aggregate