Phenotypes Associated with This Genotype

Genotype
MGI:2675269

• Allelic Composition: Hoxb3^tm1Mrc/Hoxb3^tm1Mrc
• Genetic Background: involves: 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, incomplete penetrance ( J:45337 )

• a small number of newborns are found dead soon after birth, consistent with the low frequency of the IXth cranial nerve defects

skeleton

fusion of atlas and odontoid process ( J:45337 )

• the anterior arch of the atlas is joined by an ossified bridge to the dens of the axis, low penetrance

nervous system

fusion of glossopharyngeal and vagus nerve ( J:45337 )

• partial deletion of cranial nerve IX or fusion to cranial nerve X at relatively low penetrance