Mouse Genome Informatics
hm
    EdnrbWS4/EdnrbWS4
involves: BALB/c * MSM
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       

Cochlea comparison of wild type and EdnrbWS4/EdnrbWS4 mice at 6 weeks of age

mortality/aging
• animals appear sick after two weeks of age and die between 2 and 7 weeks after birth

pigmentation
• extensive white spotting

digestive/alimentary system

hearing/vestibular/ear
• endolymphatic collapse in the cochleae

nervous system

integument
• extensive white spotting

Mouse Models of Human Disease
OMIM IDRef(s)
Waardenburg Syndrome, Type 4A; WS4A 277580 J:76584