Phenotypes Associated with This Genotype

Genotype
MGI:2669860

• Allelic Composition: Trrap^tm1.1Zqw/Trrap^tm1.1Zqw
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality before implantation, complete penetrance ( J:71950 )

• embryos die prior to E3.5

embryo

abnormal embryonic tissue morphology ( J:71950 )

absent inner cell mass ( J:71950 )

• absence of organized ICM

abnormal extraembryonic tissue morphology ( J:71950 )

abnormal trophoblast layer morphology ( J:71950 )

• trophoblast layer exhibits growth retardation

abnormal trophoblast giant cell morphology ( J:71950 )

• trophoblast cells exhibit aberrant nuclear morphology and mitotic abnormalities