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Phenotypes Associated with This Genotype
STOCK EdaTa Atp7aMo-blo/+ +
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
ArTfm mutation (2 available); any Ar mutation (17 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• indistinguishable from females
• XY mice had vaginas that remained closed in most mice, though some did open at 3 months of age
• most spermatocytes were arrested at meiotic prophase, though some were observed in metaphase
• hypertrophic
• testes were positioned amongst fat in the abdomen
• the epididymides were absent from XY mice
• the vas deferens were absent from XY mice
• XY mice possessed testes and female secondary structures including vagina and teats
• XY mice did not possess ovaries

• XY mice behaved like non-oestrus females, reduced aggression

digestive/alimentary system
• indistinguishable from females

endocrine/exocrine glands
• hypertrophic
• testes were positioned amongst fat in the abdomen

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
androgen insensitivity syndrome DOID:4674 OMIM:300068

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory