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Phenotypes Associated with This Genotype
Genotype
MGI:2665793
Allelic
Composition
ArTfm/Y
Genetic
Background
STOCK EdaTa Atp7aMo-blo/+ +
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
ArTfm mutation (3 available); any Ar mutation (17 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• indistinguishable from females
• XY mice had vaginas that remained closed in most mice, though some did open at 3 months of age
• most spermatocytes were arrested at meiotic prophase, though some were observed in metaphase
• hypertrophic
• testes were positioned amongst fat in the abdomen
• the epididymides were absent from XY mice
• the vas deferens were absent from XY mice
• XY mice possessed testes and female secondary structures including vagina and teats
• XY mice did not possess ovaries

behavior/neurological
• XY mice behaved like non-oestrus females, reduced aggression

digestive/alimentary system
• indistinguishable from females

endocrine/exocrine glands
• hypertrophic
• testes were positioned amongst fat in the abdomen

Mouse Models of Human Disease
OMIM ID Ref(s)
Androgen Insensitivity Syndrome; AIS 300068 J:5173


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory