Mouse Genome Informatics
ht
    Pafah1b1tm1Awb/Pafah1b1tm2Awb
involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• all dead by two weeks of age

growth/size

nervous system
• broad, discontinuous stratum pyrimadale
• lacked stratum oriens
• misplaced cells

Mouse Models of Human Disease
OMIM IDRef(s)
Lissencephaly 1; LIS1 607432 J:49531
Miller-Dieker Lissencephaly Syndrome; MDLS 247200 J:49531