Phenotypes Associated with This Genotype

Genotype
MGI:2661992

• Allelic Composition: Insl3^tm1Par/Insl3⁺
• Genetic Background: involves: 129/Sv * CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

cryptorchism ( J:55881 )

♂ • 75% of neonatal males had partial unilateral cryptorchism

♂ • 25% of neonatal males had partial bilateral cryptorchism

♂ • all adult males had fully descended testes

bilateral cryptorchism ( J:55881 )

♂ • 25% of neonatal males had partial bilateral cryptorchism

unilateral cryptorchism ( J:55881 )

♂ • 75% of neonatal males had partial unilateral cryptorchism

reproductive system

cryptorchism ( J:55881 )

♂ • 75% of neonatal males had partial unilateral cryptorchism

♂ • 25% of neonatal males had partial bilateral cryptorchism

♂ • all adult males had fully descended testes

bilateral cryptorchism ( J:55881 )

♂ • 25% of neonatal males had partial bilateral cryptorchism

unilateral cryptorchism ( J:55881 )

♂ • 75% of neonatal males had partial unilateral cryptorchism

abnormal gubernaculum morphology ( J:55881 )

• delayed gubernacular regression

skeleton

abnormal gubernaculum morphology ( J:55881 )

• delayed gubernacular regression

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cryptorchidism		DOID:11383	OMIM:219050	J:55881