Phenotypes Associated with This Genotype

Genotype
MGI:2660700

• Allelic Composition: Ccnb2^tm1Thnt/Ccnb2^tm1Thnt
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:47430 )

• homozygous mutants are underrepresented in F2 progeny

growth/size/body

decreased body weight ( J:47430 )

reproductive system

decreased litter size ( J:47430 )

hematopoietic system

small thymus ( J:47430 )

• thymus is somewhat smaller

increased double-negative T cell number ( J:47430 )

• slightly higher proportion of CD4-CD8 double-negative cells

immune system

small thymus ( J:47430 )

• thymus is somewhat smaller

increased double-negative T cell number ( J:47430 )

• slightly higher proportion of CD4-CD8 double-negative cells

endocrine/exocrine glands

small thymus ( J:47430 )

• thymus is somewhat smaller