Mouse Genome Informatics
ht
    Bey/Bey+
129S/SvEv-Bey
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
craniofacial
• altered facial structure is 100% penetrant in males and 75% penetrant in females
• results in an undershot jaw
• reduced nasal bone

skeleton
• altered facial structure is 100% penetrant in males and 75% penetrant in females
• results in an undershot jaw
• reduced nasal bone
• from about 2 weeks after birth

vision/eye
• 100% penetrance in males and 75% penetrance in females; bulging eyes are due to skeletal defects as eye size is normal

Mouse Models of Human Disease
OMIM IDRef(s)
Crouzon Syndrome 123500 J:47965