Mouse Genome Informatics
hm
    Slc1a1tm1Wst/Slc1a1tm1Wst
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
behavior/neurological
N
• there were no obvious neurological disorders in the first 12 months of life (J:41613)
• learning was not affected as indicated by a water maze test (J:41613)
• motor coordination was normal (J:41613)
• only about half normal level of motor activity
• shorter bursts of activity and longer stretches of inactivity

homeostasis/metabolism
• although plasma amino acid levels are normal, excretion of glutamate is increased 1400X and excretion of aspartate is increased 10X

renal/urinary system
• although plasma amino acid levels are normal, excretion of glutamate is increased 1400X and excretion of aspartate is increased 10X

Mouse Models of Human Disease
OMIM IDRef(s)
Dicarboxylic Aminoaciduria; DCBXA 222730 J:41613