Phenotypes Associated with This Genotype

Genotype
MGI:2653892

• Allelic Composition: Abl1^tm1Mlg/Abl1^tm1Mlg; Abl2^tm1Ajk/Abl2⁺
• Genetic Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality throughout fetal growth and development, incomplete penetrance ( J:51887 )

• mutants die between E15.5 and E16

cardiovascular system

hemopericardium ( J:51887 )

• seen in most mutants

pericardial edema ( J:51887 )

distended pericardium ( J:51887 )

• the pericardial sac of many mutants is enlarged and edematous

hemoperitoneum ( J:51887 )

• seen in most mutants

growth/size/body

abnormal peritoneum morphology ( J:51887 )

• the peritoneum of many mutants is enlarged and edematous

homeostasis/metabolism

hemopericardium ( J:51887 )

• seen in most mutants

edema ( J:51887 )

• peritoneum is edematous in many mutants

pericardial edema ( J:51887 )