Phenotypes Associated with This Genotype

Genotype
MGI:2652039

• Allelic Composition: Bmp15^tm1Zuk/Bmp15^tm1Zuk
• Genetic Background: involves: 129S7/SvEvBrd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

impaired ovarian folliculogenesis ( J:69611 )

♀ • reduction in numbers of follicles in occasional ovaries at various stages

ovary cyst ( J:69611 )

♀ • rare incidence of uni- and bilateral cysts at 1 yr of age

reproductive system

abnormal zona pellucida morphology ( J:69611 )

♀ • occasionally, ovaries show an increase in the number of zona pellucida remnants

impaired ovarian folliculogenesis ( J:69611 )

♀ • reduction in numbers of follicles in occasional ovaries at various stages

ovary cyst ( J:69611 )

♀ • rare incidence of uni- and bilateral cysts at 1 yr of age

reduced female fertility ( J:69611 )

♀ • Background Sensitivity: subfertility is more severe on the 129S7/SvEvBrd background than on the mixed 129S7/SvEvBrd and C57BL/6J background

decreased litter size ( J:69611 )

♀ • average litter size is 2.95 (+/- 0.30)

cellular

abnormal zona pellucida morphology ( J:69611 )

♀ • occasionally, ovaries show an increase in the number of zona pellucida remnants

growth/size/body

ovary cyst ( J:69611 )

♀ • rare incidence of uni- and bilateral cysts at 1 yr of age