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Phenotypes Associated with This Genotype
Genotype
MGI:2651823
Allelic
Composition
Lpltm1Sem/Lpl+
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lpltm1Sem mutation (0 available); any Lpl mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• mild to moderate hypertriglyceridemia without affecting static HDL cholesterol levels, both with ad libitum feeding and after fasting
• triglycerides are present as very low density lipoprotein particles and chylomicrons

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
familial lipoprotein lipase deficiency DOID:14118 OMIM:238600
J:25652


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory