Mouse Genome Informatics
hm
    Itgb2tm1Bay/Itgb2tm1Bay
involves: 129S7/SvEvBrd
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
immune system
• Background Sensitivity: increased total leukocyte counts however less elevated than on the PL/J background (J:32126)
• decreased inflammatory response to i.p. injection of thioglycollate showing decreased migration of neutrophils into the peritoneal cavity
• delayed rejection of cardiac transplants

hematopoietic system
• Background Sensitivity: increased total leukocyte counts however less elevated than on the PL/J background (J:32126)

integument
N
• Background Sensitivity: did not develop progressive dermatitis in the 129S7/SvEvBrd background (J:32126)

Mouse Models of Human Disease
OMIM IDRef(s)
Leukocyte Adhesion Deficiency, Type I; LAD 116920 J:13599