Phenotypes for Opn4 MGI:2450996 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Opn4^tm1Ruby/Opn4^tm1Ruby
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

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Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Opn4^tm1Ruby mutation (0 available); any Opn4 mutation (33 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal circadian behavior phase ( J:81502 )

• the magnitude of responses to phase shift are reduced by about 40% compared to wild-type; however homozygotes entrain normally, phase shift in response to brief light pulses, and increase circadian period with increased light intensity

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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