Phenotypes Associated with This Genotype

Genotype
MGI:2448756

• Allelic Composition: ml/ml
• Genetic Background: involves: CBA/FaCam

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:33327 )

• all homozygotes die by 18 days of age

prenatal lethality, incomplete penetrance ( J:33456 )

• low numbers of homozygous mutant offspring are probably due to death prior to birth and classification

behavior/neurological

abnormal motor capabilities/coordination/movement ( J:33327 )

• described as having a similar phenotype to Dst^dt mice

nervous system

abnormal myelination ( J:13530 )

• mutant animals severely lack myelin