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Phenotypes Associated with This Genotype
Genotype
MGI:2448372
Allelic
Composition
Spta1sph/Spta1sph
Genetic
Background
involves: C3H
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spta1sph mutation (2 available); any Spta1 mutation (11 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• none survive for more than 24 hours (J:12276)
• none survive for more than 24 hours (J:12276)

hematopoietic system
• reticulocytes do not accumulate alpha spectrin in their membranes and do not synthesize detectable amounts of alpha spectrin (J:7501)
• reticulocytes do not accumulate alpha spectrin in their membranes and do not synthesize detectable amounts of alpha spectrin (J:7501)

cardiovascular system
• livers show considerable congestion (J:12276)
• livers show considerable congestion (J:12276)

homeostasis/metabolism

liver/biliary system
• livers are much darker than in control littermates (J:12276)
• livers are much darker than in control littermates (J:12276)
• livers show considerable congestion (J:12276)
• livers show considerable congestion (J:12276)
• gradually acquire a yellow color during the first few hours of life (J:12276)
• gradually acquire a yellow color during the first few hours of life (J:12276)

integument
• extremely pale at birth (J:12276)
• extremely pale at birth (J:12276)


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory