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Phenotypes Associated with This Genotype
Genotype
MGI:2429428
Allelic
Composition
exma/Y
Genetic
Background
FVB/N-exma
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phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• no transgenic males survive beyond birth

craniofacial
• males were described as showing foreshortened craniofacial features

embryo
• male embryos were typically smaller than normal littermates

growth/size/body
• male embryos were typically smaller than normal littermates

vision/eye
• observed in 83% of embryos age E9.5- E18.5

nervous system
• disorganized forebrain
• observed in 83% of embryos age E9.5- E18.5
• cranial closure defects extended to a level caudal to the external ear indicating that in addition to forebrain and midbrain, the hindbrain neural folds failed to close normally


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory