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Phenotypes Associated with This Genotype
Genotype
MGI:2386645
Allelic
Composition
Abcb1btm2Bor/Abcb1btm2Bor
Genetic
Background
involves: 129P2/OlaHsd * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abcb1btm2Bor mutation (0 available); any Abcb1b mutation (84 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• altered pharmacokinetics of digoxin, with reduced elimination (and thus accumulation) of digoxin in adrenal glands and ovaries but not any other tissue
• rate of rhodamine efflux from hematopoietic progenitor cells is diminished


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory