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Phenotypes Associated with This Genotype
Genotype
MGI:2384175
Allelic
Composition
Trpv3Nh/Trpv3+
Genetic
Background
DS
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trpv3Nh mutation (3 available); any Trpv3 mutation (25 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• age of onset is noted as 8 weeks affecting 5-10% of mice housed under conventional conditions
• by 24 weeks of age, all mice are affected when housed under conventional conditions
• mice housed under a pathogen free barrier system do not display this phenotype
• dermatitis is caused by an increased susceptibility to Staphylococcus aureus

integument
• age of onset is noted as 8 weeks affecting 5-10% of mice housed under conventional conditions
• by 24 weeks of age, all mice are affected when housed under conventional conditions
• mice housed under a pathogen free barrier system do not display this phenotype

Mouse Models of Human Disease
OMIM ID Ref(s)
Dermatitis, Atopic 603165 J:42153


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory