Mouse Genome Informatics
hm
    Cftrtm2Hgu/Cftrtm2Hgu
involves: 129P2/OlaHsd * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
digestive/alimentary system
• focal hypertrophy of goblet cells, however do not observe distension of crypts in the small intestine or intestinal blockage
• defect in chloride ion transport in the jejunum but not the caecum

respiratory system
• defect in chloride ion transport in the nose, with baseline nasal biolelectrics significantly raised and a reduced response to a low chloride gradient

craniofacial
N
• teeth are normal in color (J:74740)

reproductive system
N
• males and females are fertile (J:74740)

Mouse Models of Human Disease
OMIM IDRef(s)
Cystic Fibrosis; CF 219700 J:74740