Mouse Genome Informatics
hm
    Amelxtm1Kul/Amelxtm1Kul
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype

Enamel hypoplasia in Amelxtm1Kul/Amelxtm1Kul incisors

craniofacial
• teeth show a chalky-white discoloration as early as 2 weeks of age
• absence of prism pattern of organized mineral crystals in enamel
• mandibular molars show an enamel thickness with less than 10% of normal enamel
• tips of incisors and molars are broken

growth/size/body
• teeth show a chalky-white discoloration as early as 2 weeks of age
• absence of prism pattern of organized mineral crystals in enamel
• mandibular molars show an enamel thickness with less than 10% of normal enamel
• tips of incisors and molars are broken

Mouse Models of Human Disease
OMIM IDRef(s)
Amelogenesis Imperfecta, Type IE; AI1E 301200 J:71126