Mouse Genome Informatics
cx
    Dmdmdx/Y
Dtnatm1Jrs/Dtnatm1Jrs

involves: 129X1/SvJ * C57BL/10ScSn
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• life span is 8-10 months (J:59675)

muscle
• develop moderate to severe cardiomyopathy (J:59675)
• exhibit a more severe dystrophy than single Dmdmdx mutant mice, but not as severe as that of double mutant Utrntm1Jrs and Dmd mdx mice or triple mutant Utrntm1Jrs, Dtnatm1Jrs, and Dmdmdx mice (J:59675)

cardiovascular system
• develop moderate to severe cardiomyopathy (J:59675)

nervous system
• at 2-4 months of age, synapses are broken into discrete boutons and acetylcholine receptors are patchily distributed within the boutons (J:60776)

Mouse Models of Human Disease
OMIM IDRef(s)
Muscular Dystrophy, Duchenne Type; DMD 310200 J:59675