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Phenotypes Associated with This Genotype
Genotype
MGI:2175712
Allelic
Composition
Atp7aMo/Atp7a+
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atp7aMo mutation (0 available); any Atp7a mutation (75 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• some survive post weaning but most die before 2 weeks of age
• partial pre-natal lethality

reproductive system
• litter size is about 25% smaller than in controls

pigmentation
(J:249)
• irregular patches of full colored and very lightly colored fur over the whole coat (J:13041)
• most female heterozygotes have mottled coats, due to the Lyon effect, inactivation of one or the other of the X chromosomes; the mutant gene is active in the light patches, the wild-type gene in the dark (J:13041)

integument
(J:249)
• irregular patches of full colored and very lightly colored fur over the whole coat (J:13041)
• most female heterozygotes have mottled coats, due to the Lyon effect, inactivation of one or the other of the X chromosomes; the mutant gene is active in the light patches, the wild-type gene in the dark (J:13041)
• curling of vibrissae although the hairs of the coat are not noticeably waved

Mouse Models of Human Disease
OMIM ID Ref(s)
Menkes Disease 309400 J:249


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory