Mouse Genome Informatics
ht
    Atp7aMo/Atp7a+
Not Specified
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• some survive post weaning but most die before 2 weeks of age (J:13041)
• partial pre-natal lethality (J:13041)

reproductive system
• litter size is about 25% smaller than in controls (J:13041)

pigmentation
(J:249)
• irregular patches of full colored and very lightly colored fur over the whole coat (J:13041)
• most female heterozygotes have mottled coats, due to the Lyon effect, inactivation of one or the other of the X chromosomes; the mutant gene is active in the light patches, the wild-type gene in the dark (J:13041)

integument
(J:249)
• irregular patches of full colored and very lightly colored fur over the whole coat (J:13041)
• most female heterozygotes have mottled coats, due to the Lyon effect, inactivation of one or the other of the X chromosomes; the mutant gene is active in the light patches, the wild-type gene in the dark (J:13041)
• curling of vibrissae although the hairs of the coat are not noticeably waved (J:249)

Mouse Models of Human Disease
OMIM IDRef(s)
Menkes Disease 309400 J:249