Phenotypes Associated with This Genotype

Genotype
MGI:2175702

• Allelic Composition: Apo/Apo⁺
• Genetic Background: involves: 101 * C3H

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

pupil opacity ( J:13942 )

• pupillary membrane opacity

corneal opacity ( J:9528 , J:13942 )

cataract ( J:9528 )

anterior polar cataract ( J:13942 )

• anterior polar opacity of the lens

abnormal eye development ( J:9528 )

• mice have remnants of the pupillary membrane present

behavior/neurological

hyperactivity ( J:13942 )

circling ( J:9528 , J:13942 )

• seen in about 30% of mutants (J:9528)

reproductive system

decreased litter size ( J:9528 )

mortality/aging

preweaning lethality, incomplete penetrance ( J:13942 )

• less than expected Mendelian ratio, indicating semilethality

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cataract		DOID:83	OMIM:601371 OMIM:PS116200	J:9528