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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Impg2em2Xjz
endonuclease-mediated mutation 2, Xianjun Zhu
MGI:6466713
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Impg2em2Xjz/Impg2em2Xjz C57BL/6J-Impg2em2Xjz MGI:6466735


Genotype
MGI:6466735
hm1
Allelic
Composition
Impg2em2Xjz/Impg2em2Xjz
Genetic
Background
C57BL/6J-Impg2em2Xjz
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Impg2em2Xjz mutation (0 available); any Impg2 mutation (42 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• astrogliosis in retina at age 6 months
• increased apoptosis at age 6 months
• increased apoptosis at age 6 months

vision/eye
• increased apoptosis at age 6 months
• increased apoptosis at age 6 months
• increasing decrease of peripheral ONL thickness at ages 6 and 12 months
• normal thickness at age 1 month
• pigment deposits and scattered patchy gray lesions of 11.5 disc diameter in retina at age 3 months

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
retinitis pigmentosa 56 DOID:0110371 OMIM:613581
J:295355





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2022
MGI 6.20
The Jackson Laboratory