Phenotypes associated with this allele

• Allele Symbol: Vangl2^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6430659
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Vangl2^em1(IMPC)Mbp/Vangl2^em1(IMPC)Mbp	C57BL/6N-Vangl2^em1(IMPC)Mbp/MbpMmucd	MGI:6696970
ht2	Vangl2^em1(IMPC)Mbp/Vangl2^+	C57BL/6N-Vangl2^em1(IMPC)Mbp/MbpMmucd	MGI:7317092

Genotype
MGI:6696970

hm1

• Allelic Composition: Vangl2^em1(IMPC)Mbp/Vangl2^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Vangl2^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Vangl2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal craniofacial morphology ( J:211773 )

IMPC - UCD

cleft palate ( J:211773 )

IMPC - UCD

abnormal head shape ( J:211773 )

IMPC - UCD

digestive/alimentary system

cleft palate ( J:211773 )

IMPC - UCD

embryo

embryonic growth retardation ( J:211773 )

IMPC - UCD

abnormal placenta morphology ( J:211773 )

IMPC - UCD

growth/size/body

cleft palate ( J:211773 )

IMPC - UCD

abnormal head shape ( J:211773 )

IMPC - UCD

embryonic growth retardation ( J:211773 )

IMPC - UCD

limbs/digits/tail

abnormal tail morphology ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

nervous system

exencephaly ( J:211773 )

IMPC - UCD

Genotype
MGI:7317092

ht2

• Allelic Composition: Vangl2^em1(IMPC)Mbp/Vangl2⁺
• Genetic Background: C57BL/6N-Vangl2^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Vangl2

embryo

abnormal placenta morphology ( J:211773 )

IMPC - UCD

homeostasis/metabolism

decreased circulating phosphate level ( J:211773 )

♂

IMPC - UCD

vision/eye

persistence of hyaloid vascular system ( J:211773 )

IMPC - UCD

microphthalmia ( J:211773 )

IMPC - UCD

abnormal retina morphology ( J:211773 )

♀

IMPC - UCD