All Phenotypes Cdh9<tm1b(KOMP)Wtsi> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cdh9^{tm1b(KOMP)Wtsi}
targeted mutation 1b, Wellcome Trust Sanger Institute
MGI:6147663

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cdh9^{tm1b(KOMP)Wtsi}/Cdh9^{tm1b(KOMP)Wtsi}	C57BL/6N-Cdh9^{tm1b(KOMP)Wtsi}/Ics	MGI:6461138
cn2	Cdh9^{tm1b(KOMP)Wtsi}/Cdh9^{tm1b(KOMP)Wtsi} Kcng4^{tm1.1(cre)Jrs}/Kcng4⁺ Tg(Thy1-EYFP)15Jrs/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N * CBA * FVB/N	MGI:6147651
cn3	Cdh9^{tm1b(KOMP)Wtsi}/Cdh9^{tm1b(KOMP)Wtsi} Neto1^{tm1.1(cre)Jrs}/Neto1⁺ Tg(Thy1-EYFP)15Jrs/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N * CBA * FVB/N	MGI:6147652

Allelic Composition	Cdh9^{tm1b(KOMP)Wtsi}/Cdh9^{tm1b(KOMP)Wtsi}
Genetic Background	C57BL/6N-Cdh9^{tm1b(KOMP)Wtsi}/Ics
Cell Lines	EPD0837_1_F03

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdh9^{tm1b(KOMP)Wtsi} mutation (0 available); any Cdh9 mutation (46 available)

Data Sources

IMPC Data for Cdh9

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased grip strength ( J:211773 )

IMPC - ICS

homeostasis/metabolism

increased circulating cholesterol level ( J:211773 )

IMPC - ICS

Allelic Composition	Cdh9^{tm1b(KOMP)Wtsi}/Cdh9^{tm1b(KOMP)Wtsi} Kcng4^{tm1.1(cre)Jrs}/Kcng4⁺ Tg(Thy1-EYFP)15Jrs/0
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N * CBA * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdh9^{tm1b(KOMP)Wtsi} mutation (0 available); any Cdh9 mutation (46 available)
Kcng4^{tm1.1(cre)Jrs} mutation (1 available); any Kcng4 mutation (24 available)
Tg(Thy1-EYFP)15Jrs mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:214586 )

N	• axonal arbors in ON-OFF direction-selective ganglion cells (ooDSGC), starburst amacrine cells (SAC), rod bipolar cells (BC), type 3a OFF BC, tyrosine-hydroxylase-positive wide-field amacrine cells, and Vglut3-positive narrow-field amacrine cells

abnormal retina bipolar cell morphology ( J:214586 )

• one-third of BC5 cells bear monostratified axonal arbors displaced into outer half of inner plexiform layer (IPL)

• two-thirds of BC5 cells bear monostratified axonal arbors in normal sublamina

• BC5 cell axonal arbors bistratified: distributed between two sublaminae

vision/eye

vision/eye phenotype ( J:214586 )

N	• axonal arbors in ON-OFF direction-selective ganglion cells (ooDSGC), starburst amacrine cells (SAC), rod bipolar cells (BC), type 3a OFF BC, tyrosine-hydroxylase-positive wide-field amacrine cells, and Vglut3-positive narrow-field amacrine cells

abnormal retina bipolar cell morphology ( J:214586 )

• one-third of BC5 cells bear monostratified axonal arbors displaced into outer half of inner plexiform layer (IPL)

• two-thirds of BC5 cells bear monostratified axonal arbors in normal sublamina

• BC5 cell axonal arbors bistratified: distributed between two sublaminae

Allelic Composition	Cdh9^{tm1b(KOMP)Wtsi}/Cdh9^{tm1b(KOMP)Wtsi} Neto1^{tm1.1(cre)Jrs}/Neto1⁺ Tg(Thy1-EYFP)15Jrs/0
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N * CBA * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdh9^{tm1b(KOMP)Wtsi} mutation (0 available); any Cdh9 mutation (46 available)
Neto1^{tm1.1(cre)Jrs} mutation (1 available); any Neto1 mutation (42 available)
Tg(Thy1-EYFP)15Jrs mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:214586 )

N	• axonal arbors in retinal type 2 bipolar cells (BC2)

vision/eye

vision/eye phenotype ( J:214586 )

N	• axonal arbors in retinal type 2 bipolar cells (BC2)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23