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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Hand2os1em1Eno
endonuclease-mediated mutation 1, Eric N Olson
MGI:5906350
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Hand2os1em1Eno/Hand2os1em1Eno C57BL/6-Hand2os1em1Eno MGI:5906409
cx2
Hand1tm1Eno/Hand1+
Hand2os1em1Eno/Hand2os1+
involves: 129S7/SvEvBrd * C57BL/6 MGI:5906410


Genotype
MGI:5906409
hm1
Allelic
Composition
Hand2os1em1Eno/Hand2os1em1Eno
Genetic
Background
C57BL/6-Hand2os1em1Eno
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

cardiovascular system
N
• unlike Hand2tm1Dsr homozygotes, mice do not exhibit vascular defects in the aortic arch arteries and the aortic sac
• left-sided

embryo

cellular
• reduced histone modifications (H3K4me1 and H3K27ac) in the heart

growth/size/body

homeostasis/metabolism




Genotype
MGI:5906410
cx2
Allelic
Composition
Hand1tm1Eno/Hand1+
Hand2os1em1Eno/Hand2os1+
Genetic
Background
involves: 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hand1tm1Eno mutation (1 available); any Hand1 mutation (3 available)
Hand2os1em1Eno mutation (0 available); any Hand2os1 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

cardiovascular system
• left-sided

growth/size/body

embryo

homeostasis/metabolism





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory