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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Anks1btm1b(KOMP)Wtsi
targeted mutation 1b, Wellcome Trust Sanger Institute
MGI:5896631
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Anks1btm1b(KOMP)Wtsi/Anks1btm1b(KOMP)Wtsi B6(FVB)-Anks1btm1b(KOMP)Wtsi MGI:5906261


Genotype
MGI:5906261
hm1
Allelic
Composition
Anks1btm1b(KOMP)Wtsi/Anks1btm1b(KOMP)Wtsi
Genetic
Background
B6(FVB)-Anks1btm1b(KOMP)Wtsi
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• loss of pups between birth and weaning

nervous system
• significant PPI deficits using a 73 dB prepulse but not at higher prepulse intensities

behavior/neurological
• enhanced sensitivity in males to ketamine's locomotor activating effects at lower doses (10 mg/kg) but similar responses at higher doses that decrease activity
• increased activity levels in an open field
• enhanced sensitivity in males to ketamine's locomotor activating effects at lower doses (10 mg/kg) but similar responses at higher doses that decrease activity
• elevated stereotypy count





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory