Phenotypes associated with this allele

• Allele Symbol: Ptchd1^{tm1b(KOMP)IcsOrl}
• Allele Name: targeted mutation 1b, Institut de Transgenose
• Allele ID: MGI:5763006
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ptchd1^tm1b(KOMP)IcsOrl/Ptchd1^tm1b(KOMP)IcsOrl	C57BL/6N-Ptchd1^tm1b(KOMP)IcsOrl/Ics	MGI:5797744
ot2	Ptchd1^tm1b(KOMP)IcsOrl/Y	C57BL/6N-Ptchd1^tm1b(KOMP)IcsOrl/Ics	MGI:5797743

Genotype
MGI:5797744

hm1

• Allelic Composition: Ptchd1^{tm1b(KOMP)IcsOrl}/Ptchd1^{tm1b(KOMP)IcsOrl}
• Genetic Background: C57BL/6N-Ptchd1^{tm1b(KOMP)IcsOrl}/Ics
• Cell Lines: G14BD10-161

Data Sources

IMPC Data for Ptchd1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal contextual conditioning behavior ( J:211773 )

♀

IMPC - ICS

abnormal cued conditioning behavior ( J:211773 )

♀

IMPC - ICS

increased exploration in new environment ( J:211773 )

♀

IMPC - ICS

hyperactivity ( J:211773 )

♀

IMPC - ICS

hematopoietic system

decreased erythrocyte cell number ( J:211773 )

♀

IMPC - ICS

homeostasis/metabolism

increased circulating creatinine level ( J:211773 )

♀

IMPC - ICS

Genotype
MGI:5797743

ot2

• Allelic Composition: Ptchd1^{tm1b(KOMP)IcsOrl}/Y
• Genetic Background: C57BL/6N-Ptchd1^{tm1b(KOMP)IcsOrl}/Ics
• Cell Lines: G14BD10-161

Data Sources

IMPC Data for Ptchd1

behavior/neurological

increased exploration in new environment ( J:211773 )

♂

IMPC - ICS

increased aggression ( J:211773 )

♂

IMPC - ICS

abnormal locomotor behavior ( J:211773 )

♂

IMPC - ICS

hyperactivity ( J:211773 )

♂

IMPC - ICS

increased vertical activity ( J:211773 )

♂

IMPC - ICS

abnormal vocalization ( J:211773 )

♂

IMPC - ICS

growth/size/body

increased lean body mass ( J:211773 )

♂

IMPC - ICS

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

♂

IMPC - ICS

hematopoietic system

abnormal spleen morphology ( J:211773 )

♂

IMPC - ICS

immune system

abnormal spleen morphology ( J:211773 )

♂

IMPC - ICS

skeleton

decreased bone mineral density ( J:211773 )

♂

IMPC - ICS